The pandemic of respiratory diseases enlightened people that monitoring respiration has promising prospects in averting many fatalities by tracking the development of diseases. However, the response speed of current optical fiber sensors is still insufficient to meet the requirements of high-frequency respiratory detection during respiratory failure. Here, a scheme for a fast and stable tachypnea monitor is proposed utilizing a water-soluble C₆₀-Lys ion compound as functional material for the tracking of humidity change in the progression of breath. The polarization of C₆₀-Lys can be tuned by the ambient relative humidity change, and an apparent refractive index alteration can be detected due to the small size effect. In our experiments, C₆₀-Lys is conformally and uniformly deposited on the surface of a tilted fiber Bragg grating (TFBG) to fabricate an ultra-fast-response, high-sensitivity, and long-term stable optical fiber humidity sensor. A relative humidity (RH) detecting sensitivity of 0.080 dB/% RH and the equilibrium response time and recovery time of 1.85 s and 1.58 s are observed, respectively. Also, a linear relation is detected between the resonance intensity of the TFBG and the environment RH. In a practical breath monitoring experiment, the instantaneous response time and recovery time are measured as 40 ms and 41 ms, respectively, during a 1.5 Hz fast breath process. Furthermore, an excellent time stability and high repeatability are exhibited in experiments conducted over a range of 7 days.